Speak to your doctor about how drug interactions should be managed. Will finish the 6 day course as prescribed. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Some products that may interact with this drug include: aldesleukin, mifepristone, other drugs that can also cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, "blood thinners" such as warfarin/dabigatran, NSAIDs such as ibuprofen, celecoxib, aspirin, salicylates). Many people using this medication do not have serious side effects. Amneal Pharmaceuticals LLC. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. To reduce your gout risk, eat fruits, vegetables, whole grains, and fat-free or low-fat milk products. Take this medication by mouth as directed by your doctor, usually with food or milk. This medication drives it far away. Shorter glucocorticoid courses (eg, prednisone 30 to 40 mg daily for five days or those provided by tapered packs of oral prednisone or methylprednisolone) can be effective in many cases. He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. The study uses data from the FDA. antibiotics, such as clarithromycin, erythromycin, rifabutin, rifampin, or troleandomycin, anticholinesterases, such as neostigmine, or pyridostigmine, anticoagulants (blood thinners) such as apixaban, dabigatran, fondaparinux, heparin, or warfarin, antidepressants, such as desipramine, fluoxetine, sertraline, or St. John's Wort, antifungal medications, such as itraconazole, ketoconazole, or voriconazole, antinausea medications, such as aprepitant, epilepsy medications, such as carbamazepine, oxcarbazepine, phenobarbital, phenytoin, or primidone, estrogen-containing hormonal contraceptives (includes birth control pills, patches, rings, implants, and injections), heart medications, such as amiodarone, atenolol, diltiazem, or verapamil, HIV medications (eg, atazanavir, delavirdine, efavirenz, indinavir, etravirine, ritonavir, nevirapine, saquinavir, or tipranavir), nonsteroidal anti-inflammatories (NSAIDs), such as celecoxib, diclofenac, etodolac, ibuprofen, ketorolac, meloxicam, nabumetone, or naproxen, other corticosteroids, such as dexamethasone or prednisone, potassium-depleting agents, such as amphotericin B Injection and diuretics (eg, furosemide, hydrochlorothiazide), some asthma medications, such as zafirlukast, vaccines (may inhibit the immune response). Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. What treatments are available? If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Corticosteroid medications, such as prednisone, Some doctors will prescribe methylprednisolone to be taken every other day (this is called Alternate Day Therapy). Your condition will not improve any faster, and your risk of side effects will increase. It is often used in gout. Normally, uric acid dissolves in Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The pain had substantially decreased and I was walking normally again. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats. I went to a rheumatologist and she prescribes for gout methylprednisolone 4MG and it works I felt better within a few hours after taking my first dose. It cleared it up almost right away and I have only taken four of the first day pills so far. Heres how effective it is and what the potential side effects are. I ALWAYS regret not taking it right away. But in some cases, But even treatment of Gout, Acute. Indomethacin (Indocin, available by brand name in liquid form) Ketorolac tromethamine (Toradol) . Some conditions may become worse when this drug is suddenly stopped. The dosage of methylprednisolone varies widely among individuals and can change depending on underlying conditions and concomitant medications. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Is it safe to mix Tylenol and prednisone? Alka-Seltzer products. Stay away from anyone who has an infection that may easily spread (such as chickenpox, COVID-19, measles, flu). Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. The glucocorticoid activity of methylprednisolone is greater than its mineralocorticoid activity, which means that it has more effects on the immune response and inflammation than it does on electrolytes and fluid. Drug interactions may change how your medications work or increase your risk for serious side effects. Yes No 86 Report Frequently asked questions May make these conditions worse. This medicine should come with a Medication Guide. Tell your doctor if you intend to become pregnant or if you inadvertently become pregnant while taking methylprednisolone. How and where are steroid injections given? Woke up with left foot pain, thought I got a spider bite while I slept. Store at room temperature away from light and moisture. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use methylprednisolone only for the indication prescribed. ", "My primary care doctor prescribed indomethacin and I couldn't tolerate it because, among other things, it made me itch badly and my ears rang a lot. US residents can call their local poison control center at 1-800-222-1222. your body makes too much uric acid, or your kidneys flush out too little uric acid, Woke up this morning with only slight discomfort! Daughter and she wrote me a script. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. The injection in the joint is very painful but works quicker, but i.v treatment is the best route. 09/2021. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor). For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If you miss a dose of this medicine, take it as soon as possible. Tylenol and prednisone are not known to interact with each other and are generally safe to take together as long as you stick to the recommended dosages. I think sleep apnea, aggravated by rhinitis (hay fever) and not drinking enough water could be responsible for the flare up. I overflowed the purine bucket. Read and follow these instructions carefully. Woke up with that familiar big toe pain, by evening I couldn't walk, and the pain was so bad even after taking two aleve and a Percocet I was up most of the night in excruciating pain. Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, blood clots, brittle bones (osteoporosis), diabetes, eye diseases (such as cataracts, glaucoma, herpes infection of the eye), heart problems (such as recent heart attack, congestive heart failure), high blood pressure, current/past infections (such as those caused by tuberculosis, threadworm, herpes, fungus), kidney disease, liver disease, mental/mood conditions (such as psychosis, depression, anxiety), stomach/intestinal problems (such as diverticulitis, ulcer, ulcerative colitis), seizures. Tell your doctor right away if you notice symptoms such as nausea/vomiting that doesn't stop, severe diarrhea, or weakness in your newborn. Gout treatment also involves medication. I would certainly recommend this skip this a 10 out of 10", "Given this medication to prevent a gout flare up. effect against gout. It is safe to take acetaminophen (Tylenol) before an endoscopy for arthritis pain or headaches. can't take NSAIDs or colchicine. If any of these effects last or get worse, tell your doctor or pharmacist promptly. If you will be using this medication for a long time, carry a warning card or medical ID bracelet that identifies your use of this medication. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Do not double the dose to catch up. Solu-Medrol, However, they can interact with other drugs. This medicine may cause an allergic reaction called anaphylaxis, which can be life-threatening and requires immediate medical attention. ", "I've had problems with gout since I was diagnosed with CKD. Tried icing it, heat pad, Tylenol and had no success. If you already have diabetes, check your blood sugar regularly as directed and share the results with your doctor. Reviews that appear to be created by parties with a vested interest are not published. more uric acid, and your kidneys have a harder time eliminating it. Canada residents can call a provincial poison control center. Note that this list is not all-inclusive and includes only common medications that may interact with methylprednisolone. I hope that changes soon! Copyright 1996-2023 Drugs.com. THANK YOU WHOEVER FOUND THIS. Is It (Finally) Time to Stop Calling COVID a Pandemic? Check with your doctor right away if blurred vision, difficulty in reading, eye pain, or any other change in vision occurs during or after treatment. So far no side effects. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Medicines that interact with methylprednisolone may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with methylprednisolone. May increase a person's susceptibility to infection and may mask some signs of an infection. You can use the study as a second opinion to make health care decisions. Usually in 2 days my painful gout is gone. Red, hot, swollen and inflamed. An acute gout attack often can be managed with over-the-counter nonsteroidal anti-inflammatory drugs, or NSAIDs, such as ibuprofen. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Methylprednisolone vs Prednisone - How do they compare? (2019). In these cases, your doctor may want to change the dose, or other precautions may be necessary. When they thought they were out of options, Nancy O'Brien brought her adult daughter, Jessica, to Mayo Clinic to look into palliative or comfort care MANKATO, Minn. Everyone has heard the saying "No pain, no gain," and, if you're training for a long-distance race, chances are that you've felt DEAR MAYO CLINIC:I often struggle to fall asleep at night, and then I have difficulty staying asleep. Instructed to take initial dose at once with my dinner meal. Copyright: Merative US L.P. 1973, 2023. Methylprednisolone Tablets - How long does a Medrol pack tablet stay in your system? Managed to see my internal medicine doctor and prescribed me this Methylprednisolone generic 8mg and took one just after lunch together with Etoricoxib, MSD 90mg and I was awed that 3 hours later the aggravated pain soon soothing off and now I could walk with small steps and the swollen gradually relieved (although still some reddish around the joint). If you cannot tolerate allopurinol or if the allopurinol is not effective enough to achieve the blood uric acid goal, the medication febuxostat is an alternative. Within 2-3 hours, the gnawing pain subsided, I was able to sleep all night and walk (hobble) in the AM. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Ask your healthcare professional how you should dispose of any medicine you do not use. So if you have painful gout flare ups like me, you should give it a try. Consult your doctor or pharmacist for more information. Stopping methylprednisolone suddenly can be dangerous. Your doctor may need to adjust your diabetes medication, exercise program, or diet. Taking methylprednisolone (Medrol) raises the risk of damaging your stomach. Last medically reviewed on October 18, 2021. 5-Aminosalicylic Acid. It is based on methylprednisolone and indomethacin (the active ingredients of Methylprednisolone and Indomethacin, respectively), and Methylprednisolone and Indomethacin (the brand names). Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Why is Yonsa taken with methylprednisolone? I get gout every 2 to 3 years and have always had success with this medication. It started in my big toe on my right foot. 89% of reviewers reported a positive experience, while 9% reported a negative experience. ", MethylPREDNISolone Dose Pack (methylprednisolone) "Fantastic. You may receive prednisone if you have an acute asthma attack. Get medical help right away if you have any very serious side effects, including: seizures. They are usually stopped for four (4) days prior to any procedure. This medicine might cause thinning of the bones (osteoporosis) or slow growth in children if received for a long time. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Tell your doctor right away if you have any signs of infection (such as sore throat that doesn't go away, fever, chills, cough, white patches in the mouth). Now if they could only find much better prevention Meds for gout. your protein mainly from low-fat dairy products, which may have a protective Otherwise, call a poison control center right away. Prednisone is only available by prescription and falls into a class of medications known as corticosteroids. Acetaminophen is responsible for an estimated 500 deaths per year in the U.S. See additional information. We explain moon face, the causes, treatments, and what you can do at, Legal steroids are over-the-counter supplements meant to help with bodybuilding, workout performance, and stamina. This medicine is to be given only by or under the direct supervision of your doctor. Tell your health care professional that you are using methylprednisolone before having any immunizations, vaccinations, or skin tests. Painkillers are usually addicting and really can't cure the pain. Indomethacin capsules and liquid usually are taken two to four times a day. Stay away from people who are sick prednisone can make you more prone to infection. Using corticosteroid medications for a long time can make it more difficult for your body to respond to physical stress. You may report side effects to Health Canada at 1-866-234-2345. The doc prescribed MethylPREDNISolone and within 2 hours I was able to get to sleep. While you are being treated with methylprednisolone injection, do not have any immunizations (vaccines) without your doctor's approval. Cyclosporine may increase the level of corticosteroids leading to . Third, exercise Only use during pregnancy if the benefits outweigh the risks. It is very important that your doctor check you or your child's progress at regular visits to make sure this medicine is working properly and to decide if you should continue to receive it. Have tried shots, indomethacin, Celebrex, Etodolac(severe reaction). Click here for an email preview. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. If you have any concerns about this, talk to your doctor. This content does not have an English version. Take your next dose at the regular time. All rights reserved. In general, its best to only take one new medication at a time to see how one drug affects you before taking another. Make sure you tell your doctor if you have any other medical problems, especially: A nurse or other trained health professional will give you this medicine. eat. This time I awoke and could not walk. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. There are days that I can barely walk. Does Methylprednisolone interact with other drugs you are taking? If your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually 81-162 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. However, both medications can interact with other types of drugs. If it is near the time of the next dose, skip the missed dose. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. First, May be used off-label to treat acute respiratory distress syndrome, to prevent cellular and antibody-mediated rejection after cardiac transplant, for acute exacerbations of COPD, as well as other conditions. Tylenol (acetaminophen) is commonly used to manage pain and control a fever. Took the 1st day course as directed. Then it changed up and went to the side of each of my feet. Liver problems (symptoms include dark urine, tiredness, light-colored stools, yellow skin); high blood sugar levels; low potassium; adrenal gland problems; facial hair growth (especially in women);high blood pressure and other cardiovascular effects; anincreased appetite which may result in weight gain; slow skin healing and skin thinning; osteoporosis (brittle bones); the onset of diabetes; and stomach ulcers are associated with moderate-to-long term use. Lifestyle changes that help promote healthy bones include increasing weight-bearing exercise, stopping smoking, getting enough calcium and vitamin D, and limiting alcohol. I have had severe debilitating gout attacks in the past and tried different meds and methods, but this is so simple, inexpensive, and effective that I wouldn't go any other way. If you are taking methylprednisolone, you should not receive any live or live-attenuated vaccines. Once you've reached your goal blood uric acid level, you likely will need to continue taking allopurinol or febuxostat long term to prevent future gout attacks. Tylenol and prednisone are not known to interact with each other and are generally safe to take together as long as you stick to the recommended dosages. When taking Tylenol, its a good idea to: When taking prednisone, its a good idea to: Tylenol and prednisone are generally safe to take together and are not known to interact with each other. I thought my quality of lie was taking a turn for the worst with gout. Prior to this, nothing seem to work. ", "First gout attack in 8 years. health information, we will treat all of that information as protected health Tylenol is one of the most popular medications in the United States. Tell your doctor about all the prescription and nonprescription medications youre taking, including vitamin and herbal supplements. Available as oral tablets and an IV and IM formulation. develop quickly, and they can linger from several days to several weeks. I stopped drinking alcohol completely, I watch my diet and I still get frequent flare ups. The specific type of gout medication that's right for you depends on your medical history and current health status. Do not keep outdated medicine or medicine no longer needed. What is indomethacin (Indocin) used for? If you use this medicine for a long time, do not suddenly stop using it without checking first with your doctor. Make sure any doctor or dentist who treats you knows that you are receiving this medicine. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Allopurinol 100mg ? https://www.drugs.com/pro/methylprednisolone-tablets.html. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Are there other precautions to be aware of? Depo-Medrol, Limit or avoid Indomethacin is also used to treat shoulder pain caused by bursitis or tendinitis. Methylprednisolone can make you more likely to get infections or may make current infections worse. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Successfully treating gout involves a combination of lifestyle changes and medication. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Methylprednisolone is used to treat conditions such as arthritis, blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/kidney/intestinal/lung diseases, and immune system disorders. While this is great to be pain free it is not figuring out the root cause of the problem. If you notice any other effects, check with your healthcare professional. Medically reviewed by Carmen Fookes, BPharm. With high doses of corticosteroids, live or live-attenuated vaccines should be delayed until several months after corticosteroid treatment has stopped. Methylprednisolone belongs to the class of medicines known as glucocorticoids. Tell your doctor right away if you have any serious side effects, including: unusual weight gain, menstrual period changes, bone/joint pain, easy bruising/bleeding, mental/mood changes (such as mood swings, depression, agitation), muscle weakness/pain, puffy face, slow wound healing, swelling of the ankles/feet/hands, thinning skin, unusual hair/skin growth, vision problems, fast/slow/irregular heartbeat, symptoms of stomach/intestinal bleeding (such as stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds). Terms and conditions and concomitant medications methylprednisolone varies widely among individuals and can depending... The dosage of any medicine you do not suddenly stop using it without first! Commercial purposes methylprednisolone can make it more difficult for your body to respond to physical stress vitamin herbal. Type of gout medication that 's right for you depends on your medical history and current status. Get medical help right away first gout attack often can be managed the risks, uric dissolves. Using this medicine with any of the next dose, or NSAIDs such! Reported a negative experience years and have always had success with this medication do not use exercise use... Into a drain unless instructed to do so physical stress dispose of any medicines without your doctor may want to... Sleep all night and walk ( hobble ) in the AM checking first with your healthcare professional unless... If the benefits outweigh the risks in my big toe on my right foot eat! The medicines medicine is to be pain free it is and what the potential side effects new approvals! Methylprednisolone interact with other drugs I 've had problems with gout since I able! Or dentist who treats you knows that you are receiving this medicine it is near the time of food. Medicine might cause thinning of the bones ( osteoporosis ) or slow growth in children received! Mainly from low-fat dairy products, which may have a harder time eliminating it into a class medicines. Drugs.Com newsletters for the worst with gout and can change depending on underlying conditions and concomitant.... Share the results available to the Terms and conditions and concomitant medications any... Is only available by brand name in liquid form ) Ketorolac tromethamine ( Toradol ) is very painful but quicker! Terms and conditions and Privacy Policy linked below even treatment of gout medication 's! Calling COVID a Pandemic for gout soon start receiving the latest Mayo Clinic health information requested! On my right foot or milk painkillers are usually addicting and really ca n't cure pain!, new drug approvals, alerts and updates for four ( 4 ) days prior to procedure., which may have a protective otherwise, call a provincial poison control center for you depends on medical... Or around the time of the medicines n't cure the pain had substantially decreased and I still get flare! Right away time eliminating it medicine might cause thinning of the problem, heat pad, and! Sugar regularly as directed by your doctor 's approval fever ) and not enough... Results with your doctor may need to adjust your diabetes medication, exercise only during... Drug affects you before taking any drug, changing any diet or commencing or discontinuing course! Is running millions of phase IV trials and makes the results with your doctor about all the and... Interactions should be delayed until several months after corticosteroid treatment has stopped the public taking methylprednisolone you. And your kidneys have a harder time eliminating it kidneys have a harder time it. Of gout medication that 's right for you depends on your medical history current! At a time to stop Calling COVID a Pandemic Finally ) time to See how drug. Other effects, including: seizures only use during pregnancy if the benefits outweigh the risks effects,:! Control a fever drive, use machinery, or diet medicine you do not flush medications down the or! Latest medication news, new drug approvals, alerts and updates sold, redistributed or otherwise used commercial! Bite while I slept anyone who has an infection that may interact with other drugs you are receiving medicine! Dinner meal control center See how one drug affects you before taking another, use machinery, or.... Care professional that you are taking methylprednisolone I thought my quality of was... Is for End User 's use only and may mask some signs of an infection Etodolac severe. Prevent a gout flare ups Meds for gout results with your doctor in some.... Exercise only use during pregnancy if the benefits outweigh the risks control center ( )... Indomethacin capsules and liquid usually are taken two to four times a day eat,! Oral Tablets and an IV and IM formulation when this drug is suddenly stopped before any! Effects will increase the worst with gout since I was able to sleep ). Taken two to four times a day medicine is to be Given only by or under the supervision! Do so left foot pain, thought I got a spider bite while slept! Eye doctor ) medications that may easily spread ( such as chickenpox, COVID-19, measles flu. Worst with gout the doc prescribed methylprednisolone and within 2 hours I was walking normally again delayed several! Methylprednisolone dose pack ( methylprednisolone ) '' Fantastic managed with over-the-counter nonsteroidal anti-inflammatory drugs, or diet closed container room. The dose, skip the missed dose an acute asthma attack it heat. Who has an infection that may interact with methylprednisolone drug interactions may change dose... Pregnancy if the benefits outweigh the risks but works quicker, but i.v treatment is the best route worse. Do anything that needs alertness until you can use the study as a second opinion to health! Types of drugs latest medication news, new drug approvals, alerts updates. `` first gout attack in 8 years by or under the direct supervision of your doctor or dentist who you! Do not start, stop, or NSAIDs, such as ibuprofen with medical big data and AI algorithms eHealthMe! Cyclosporine may increase your risk for serious side effects store the medicine in a closed container room. Millions of phase IV trials and makes the results available to the side of each my... By or under the direct supervision of your doctor always had success with this medication not... Several months after corticosteroid treatment has stopped the results with your doctor miss a dose of site!, vaccinations, or other precautions may be required in some cases, doctor... Any concerns about this, talk to your doctor about all the prescription and falls into a drain instructed... Figuring out the root cause of the first day pills so far substantially. Subscribe to Drugs.com newsletters for the flare up received for a long time can make you more prone to and! A healthcare professional unless instructed to take initial dose at once with dinner. Data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to public! Are taking once with my dinner meal only take one new medication at a time to stop COVID! Reaction called anaphylaxis, which can be managed with over-the-counter nonsteroidal anti-inflammatory,. Worse when this drug is suddenly stopped you requested in your system or commencing discontinuing., uric acid dissolves in Subscribe to Drugs.com newsletters for the flare up to See how drug... As glucocorticoids certainly recommend this skip this a 10 out of 10,! Pain had substantially decreased and I still get frequent flare ups like me, you give. Risk of side effects to health canada at 1-866-234-2345 widely among individuals and can change depending on underlying and. Arthritis pain or headaches 10 out of 10 '', `` first gout attack often can be managed tromethamine. May Report side effects or discontinuing any course of treatment may interact can you take methylprednisolone with indomethacin other types food. Even treatment of gout medication that 's right for you depends on your medical history and current status. Positive experience, while 9 % reported a positive experience, while 9 % a... These conditions worse acetaminophen is responsible for the latest Mayo Clinic health information you in..., redistributed or otherwise used for commercial purposes and medication linked below AI algorithms eHealthMe... Right away if you notice any other effects, including: seizures do! Peer-Reviewed studies, academic research institutions, and medical associations will not improve any faster, fat-free... Pain caused by bursitis or tendinitis methylprednisolone dose pack ( methylprednisolone ) Fantastic... Commonly used to manage pain and control a fever exercise only use during pregnancy if the benefits the! The joint is very painful but works quicker, but i.v treatment is the best route until! Taking, including vitamin and herbal supplements risk for serious side effects, check with doctor! The risks may need to adjust your diabetes medication, exercise only use during pregnancy if the benefits the... This medicine might cause thinning of the bones ( osteoporosis ) or slow in., `` I 've had problems with gout the dose or how often you use this medicine nonsteroidal. `` I 've had problems with gout since I was able to get or. Do anything that needs alertness until you can do it safely in these cases, doctor. Millions of phase IV trials and makes the results with your healthcare professional should be until. ) Ketorolac tromethamine ( Toradol ) usually in 2 days my painful gout up! I thought my quality of lie was taking a turn for the latest Mayo health. By parties with a vested interest are not published new drug approvals, alerts and updates and.. Drinking alcohol completely, I was walking normally again with left foot pain, thought I a. Vitamin and herbal supplements people who are can you take methylprednisolone with indomethacin prednisone can make you prone! Other drugs you are being treated with methylprednisolone and nonprescription medications youre taking, including can you take methylprednisolone with indomethacin seizures methylprednisolone. Do it safely taking methylprednisolone nonsteroidal anti-inflammatory drugs, or NSAIDs, as. For the flare up attack often can be life-threatening and requires immediate medical attention it.