Aged garlic extract and its constituents inhibit Cu2+ -induced oxidative modification of low density lipoprotein. Kannar D. Clinical evaluation of Australian based garlic and its combination with inulin in mild and moderate hyperlipidaemia [dissertation] . Sumioka I, Matsura T, Yamada K. Therapeutic effect of S-allylmercaptocysteine on acetaminophen-induced liver injury in mice. View abstract. View abstract. Effect of supplementation with garlic oil on activity of Th1 and Th2 lymphocytes from rats. Taking garlic along with medications that lower blood pressure might cause blood pressure to go too low. Effect of aged garlic extract on APP processing and tau phosphorylation in Alzheimer's transgenic model Tg2576. Agents Actions 1990;29(3-4):360-363. Contact Dermatitis 1996;35:157-62. View abstract. Meher S, Duley L. Garlic for preventing pre-eclampsia and its complications. View abstract. Z Phytother 1984;5:938-942. J Clin Biochem Nutr 2020;67(3):297-301. View abstract. *Percent Daily Values are based on a 2,000 calorie diet. Seitan Nutrition: Benefits, Side Effects, 14 Serious Side Effects Of Olive Oil You Should Know About, 14 Side Effects Of Eating Too Many Bananas, Flax Seed Side Effects: 6 Ways It May Cause Harm, 14 Health Benefits Of Artichoke, Nutrition, & Side Effects, Health Benefits Of Garlic Oil, Side Effects, And How To Use It. Shakeel, M., Trinidade, A., McCluney, N., and Clive, B. Complementary and alternative medicine in epistaxis: a point worth considering during the patient's history. The effect of garlic supplements on the pharmacokinetics of saquinavir. J.Food Sci. 2016;32(1):33-40. J Nutr.Biochem. Effects of Allium sativum (garlic) on systolic and diastolic blood pressure in patients with essential hypertension. Groppo, F. C., Ramacciato, J. C., Motta, R. H., Ferraresi, P. M., and Sartoratto, A. Antimicrobial activity of garlic against oral streptococci. View abstract. Relationship between consumption of raw garlic and handgrip strength in a large-scale adult population. Kandziora J. Blutdruck and lipidsenkende Wirkung eines Knoblauch-praparates in kombination mit einem Diuretikum. View abstract. Call your doctor for medical advice about side effects. 2016;25(4):624-33. Rotzsch W, Richter V, Rassoul F, Walper A. Reduction in elevated blood lipids in hospitalised patients by a standardised garlic preparation. 2015;28(3):414-23. Effect of garlic (Allium sativum) on blood lipids, blood sugar, fibrinogen and fibrinolytic activity in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty Acids 2000;62:55-73. The effect of garlic oil on lipid peroxidation and blood cell counts of arsenic exposed albino mice. Yuncu, M., Eralp, A., and Celik, A. View abstract. 1991;21(2):497-502. View abstract. Garlic intake and gastric cancer risk: Results from two large prospective US cohort studies.International journal of cancervol. Zeng T, Guo FF, Zhang CL, et al. Hype about glucosamine. However, anecdotal evidence suggests that spicy foods like onion, garlic, and ginger may make you pee more. The Cleveland Clinic also identified garlic as a potential trigger for headaches. Oral Health Prev.Dent. Garlic could trigger heartburn and irritate the digestive tract. Roussos AP, Hirsch AR. These side effects are often worse with raw garlic. 2001;67(1):475-480. Demirkaya, E., Avci, A., Kesik, V., Karslioglu, Y., Oztas, E., Kismet, E., Gokcay, E., Durak, I., and Koseoglu, V. Cardioprotective roles of aged garlic extract, grape seed proanthocyanidin, and hazelnut on doxorubicin-induced cardiotoxicity. View abstract. Garlic as a tick repellent. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 2020;13:2389-2397. 1998;30(1):189-191. Phytother Res 1991;5:154-158. Effect of garlic supplementation on plasma lipids in hypercholesterolemic men and women. J Nutr. Ide N, Lau BH. View abstract. Similarly, a Chinese study of several hundred lung cancer patients found that regular consumption of raw garlic was associated with a lower risk of lung cancer. To avoid the potential of developing skin lesions where you came in contact with the garlic, they recommend wearing protective gloves. Modulation of lipid profile by fish oil and garlic combination. Ann.Pharmacother. Horie T, Matsumoto H, Kasagi M, et al. Kodali RT, Eslick GD. Phytother Res 2021 Jan 23. doi: 10.1002/ptr.7021. A multicenter placebo-controlled double-blind study. 2005;50(7):645-651. Which Is Healthier, Raw or Cooked Garlic? View abstract. J Nutr 2001;131:985S-8S. Neuroscience 2003;122(4):885-895. Life Sci 1998;62:71-7. anonymous. Jepson RG, Kleijnen J, and Leng GC. View abstract. Contact Dermatitis 2006;55(3):193-194. View abstract. View abstract. View abstract. View abstract. Alliaceous migraines.Headachevol. Asia Pac.J Clin Nutr. Effects of garlic powder and garlic oil preparations on blood lipids, blood pressure and well-being. View abstract. J Am Coll Nutr 2001;20(3):225-231. View abstract. Although not all side effects are known, garlic is thought to be possibly safe when taken for a short period of time. German, K., Kumar, U., and Blackford, H. N. Garlic and the risk of TURP bleeding. However, low doses of garlic (0.1 grams to 0.25 grams per kg of body weight) on a daily basis are safe for the liver (2). Clin Experiment Ophthalmol 2002;30:303-4. A., Nedosugova, L. V., Filatova, L. V., Balabolkin, M. I., Gorchakova, T. V., and Orekhov, A. N. Metabolic effects of time-released garlic powder tablets in type 2 diabetes mellitus: the results of double-blinded placebo-controlled study. The results suggest that caution must be exercised before using garlic and related products as they may have undesirable effects on gastric health. Choudhary PR, Jani RD, Sharma MS. Effect of raw crushed garlic (Allium sativum L.) on components of metabolic syndrome. Carden SM, Good WV, Carden PA, Good RM. 2005;57(5):623-630. Planta Med 1994;60(3):214-217. Luley C, Lehmann-Leo W, Moller B, et al. 1991;29(4):151-155. Dirsch VM, Kiemer AK, Wagner H, Vollmar AM. View abstract. 2020;34(11):2953-2962. View abstract. Morales-Gonzlez, Jos Antonio et al. Atherosclerosis 1987;64:109-115. Hsu, C. C., Huang, C. N., Hung, Y. C., and Yin, M. C. Five cysteine-containing compounds have antioxidative activity in Balb/cA mice. Randomized comparative study with terbinafine. View abstract. JAMA 11-11-1998;280(18):1568. Rivlin, R. S. Historical perspective on the use of garlic. Phytother.Res. Int Arch.Allergy Immunol. View abstract. Occupational protein contact dermatitis in food handlers. 2010;9:119. Hubbard VG, Goldsmith P. Garlic-fingered chefs. Prev.Med 2004;39(5):985-991. Allergic contact dermatitis to garlic in a cook. No studies suggest that garlic increases the frequency of peeing or the volume of urine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. [The effects of garlic powder on cutaneous microcirculation. Therefore, those who already have the problem of bad breath should not eat garlic too much. Gravas S, Tzortzis V Rountas C Melekos MD. Durak I, Yilmaz E, Devrim E, et al. Anything in excess can be unhealthy and harmful for you, and so is garlic. Cancer 6-1-1993;71(11):3575-3581. View abstract. Apitz-Castro, R., Escalante, J., Vargas, R., and Jain, M. K. Ajoene, the antiplatelet principle of garlic, synergistically potentiates the antiaggregatory action of prostacyclin, forskolin, indomethacin and dypiridamole on human platelets. View abstract. Andrianova, I. V., Fomchenkov, I. V., and Orekhov, A. N. [Hypotensive effect of long-acting garlic tablets allicor (a double-blind placebo-controlled trial)]. 2008. Taking garlic may stimulate this nerve to release neuronal signaling molecules called neuropeptides that rush to the membrane covering your brain and cause headaches. Treatment of hyperlipidaemia with garlic-powder tablets. Atherosclerosis 1988;74(3):247-249. Warfarin is used to slow blood clotting. View abstract. Excessive intake of garlic can cause low blood pressure. A., Breckler, L., Hale, J., Lehmann, H., Franklin, P., Lyons, G., Ching, S. Y., Mori, T. A., Barden, A., and Prescott, S. L. Supplementation with vitamins C, E, beta-carotene and selenium has no effect on anti-oxidant status and immune responses in allergic adults: a randomized controlled trial. Mennella JA, Beauchamp GK. Phytomedicine 1999;6(1):7-11. View abstract. Garlic has been used safely for up to 7 years. It can cause side effects such as bad breath, heartburn, gas, and diarrhea. These side effects are often worse with raw garlic. Garlic might also increase the risk of bleeding and cause allergic reactions in some people. 54,2 (2014): 378-82. Arch Intern Med 1998;158:1189-94. bland foods such as rice, bananas or bread, National Center for Complementary and Integrative Health: "Garlic", Consumer Reports: "The Health Benefits of Garlic", Cleveland Clinic: "6 Surprising Ways Garlic Boosts Your Health", Mayo Clinic: "Herbal Supplements and Heart Medicines May Not Mix". J Int Soc Sports Nutr 2013;10(1):22. 7-15-1992;136(2):178-191. View abstract. Ahmad, M. S., Pischetsrieder, M., and Ahmed, N. Aged garlic extract and S-allyl cysteine prevent formation of advanced glycation endproducts. Garlic may increase the risk of bleeding. According to the Cleveland Clinic, you may also experience a stinging feeling on your hands from handling raw or powdered garlic. Bhuvaneswari, V., Abraham, S. K., and Nagini, S. Combinatorial antigenotoxic and anticarcinogenic effects of tomato and garlic through modulation of xenobiotic-metabolizing enzymes during hamster buccal pouch carcinogenesis. View abstract. Urol.Int. Farnsworth N, Bingel A, Cordell G, et al. View abstract. Effect of garlic on blood pressure: A systematic review and meta-analysis. J Med Food 2009;12(4):776-781. Scand.J Urol.Nephrol. Hu, J., Nyren, O., Wolk, A., Bergstrom, R., Yuen, J., Adami, H. O., Guo, L., Li, H., Huang, G., Xu, X., and . It can also cause heartburn, upset stomach, and diarrhea. 8-16-2002;2:16. Nutr.Cancer 1990;13(3):201-207. A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids. 2006;136(3 Suppl):813S-815S. However, some studies have suggested that raw garlic may be more effective than the cooked version, while garlic supplements are the most effective. Garlic and the strabismus surgeon. Carcinogenesis 2002;23(4):573-579. Lipids Health Dis. A., and Pivovarova, E. M. Direct anti-atherosclerosis-related effects of garlic. Int J Food Sci Nutr 2011;62(3):219-225. Delaney, T. A. and Donnelly, A. M. Garlic dermatitis. Breast Cancer Res Treat 1995;33:163-70. J Ethnopharmacol 2001;76:229-32.. View abstract. Ann Med 1995;27(1):63-65. Alhashim M, Lombardo J. Forsch.Komplementmed. 2002;52(6):433-437. Dietary intake of garlic and other Allium vegetables and breast cancer risk in a prospective study of postmenopausal women. Effects of garlic (Allium sativum L.) supplementation on cytochrome P450 2D6 and 3A4 activity in healthy volunteers. Tsai, Y., Cole, L. L., Davis, L. E., Lockwood, S. J., Simmons, V., and Wild, G. C. Antiviral properties of garlic: in vitro effects on influenza B, herpes simplex and coxsackie viruses. Kandziora J. Antihypertensive Wirksamkeit und Vertraglichkeit eines Knoblauch-preparates. Trop.Biomed. That way, you can get the maximum benefit of allicin, the compound in garlic responsible for its beneficial effects. View abstract. 1990;49(2):175-180. View abstract. Br.J.Nutr. Garlic powder tablets reduce atherogenicity of low density lipoprotein. Mil.Med 2003;168(6):499-500. Isaacsohn JL, Moser M, Stein EA, et al. J Food Sci 2009;74(7):R84-R91. Wang, Z. Y., Boice, J. D., Jr., Wei, L. X., Beebe, G. W., Zha, Y. R., Kaplan, M. M., Tao, Z. F., Maxon, H. R., III, Zhang, S. Z., Schneider, A. J.Burn Care Res. If you dont usually eat garlic, you may want to check with your doctor before adding it to your diet. Bradley R, Endres J, Hockenberry D, and et al. WebHowever, consuming excessive amounts of garlic can have adverse effects on your health. View abstract. Arztezeitschr Naturheilverf 1996;37:126-129. Can J Cardiol 2011;27(4):488-505. Leelarungrayub, N., Rattanapanone, V., Chanarat, N., and Gebicki, J. M. Quantitative evaluation of the antioxidant properties of garlic and shallot preparations. Effect of garlic on total serum cholesterol. Planta Med 1986;(3):163-168. Adler AJ, Holub BJ. J Pharm Pharmaceut Sci 2001;4:176-84. . De, B. K., Dutta, D., Pal, S. K., Gangopadhyay, S., Das, Baksi S., and Pani, A. Antimicrob.Agents Chemother 1988;32(12):1763-1768. J Pharm Pharmacol 1997;49:908-11. Arch Dermatol.Res 2003;295(3):117-123. J Investig Allergol Clin Immunol. Garlic might change how quickly the liver breaks down these medications. Breithaupt-Grogler K, Ling M, Boudoulas H, Belz GG. Kim H, Keum N, Giovannucci EL, Fuchs CS, Bao Y. Garlic intake and gastric cancer risk: results from two large prospective US cohort studies. Berspalov, V. G., Shcherbakov, A. M., Kalinovskii, V. P., Novik, V. I., Chepik, O. F., Aleksandrov, V. A., Sobenin, I. Cochrane.Database.Syst.Rev. 2007;25(4):164-168. Ernst E. Is garlic an effective treatment for Helicobacter pylori infection? View abstract. Canduela, V., Mongil, I., Carrascosa, M., Docio, S., and Cagigas, P. Garlic: always good for the health? View abstract. View abstract. Karabacak E, Aydin E, Kutlu A, Dogan B. Hyphema may also cause permanent vision loss. View abstract. Henning, S. M., Zhang, Y., Seeram, N. P., Lee, R. P., Wang, P., Bowerman, S., and Heber, D. Antioxidant capacity and phytochemical content of herbs and spices in dry, fresh and blended herb paste form. Alliaceous migraines. Sigounas G, Hooker J, Anagnostou A, Steiner M. S-allylmercaptocysteine inhibits cell proliferation and reduces the viability of erythroleukemia, breast, and prostate cancer cell lines. View abstract. View abstract. View abstract. Arora RC, Arora S. Comparative effect of clofibrate, garlic and onion on alimentary hyperlipemia. Mansell P, Reckless PD, and Lloyd L. The effect of dried garlic powder tablets on serum lipids in non-insulin dependent diabetic patients. Sunter WH. Lau BH, Tadi PP, and Tosk JM. Kundakovic, T., Milenkovic, M., Zlatkovic, S., Nikolic, V., Nikolic, G., and Binic, I. 2005;19(1):84-89. Select a condition to view a list of vitamins. Wohlrab, J., Wohlrab, D., and Marsch, W. C. Acute effect of a dried ethanol-water extract of garlic on the microhaemovascular system of the skin. A randomized placebo-controlled double-blind cross-over study in apparently healthy subjects. View abstract. Soleimani D, Parisa Moosavian S, Zolfaghari H, Paknahad Z. Journal of Natural Remedies 2006;6:19-25. View abstract. View abstract. Researchers at Emory University School of Medicine found that a component of garlic oil, diallyl trisulfide, helps protect the heart after a heart attack and during heart surgery. Anim-Nyame, N., Sooranna, S. R., Johnson, M. R., Gamble, J., and Steer, P. J. Garlic supplementation increases peripheral blood flow: a role for interleukin-6? However, it is typically recommended to only have 1-2 raw garlic cloves in a day.. View abstract. View abstract. Peleg, A., Hershcovici, T., Lipa, R., Anbar, R., Redler, M., and Beigel, Y. Holden C. Fighting parasites with garlic. 2006;84(4):912-919. Tutakne, M. A., Satyanarayanan, G., Bhardwaj, J. R., and Sethi, I. C. Sporotrichosis treated with garlic juice. J Epidemiol 1999;9:297-305. Pedraza-Chaverri J, Tapia E, Medina-Campos ON, et al. Reuter HD and Sendl A. Allium sativum and Allium ursinum: chemistry, pharmacology and medicinal applications. 2006;20(1):21-27. View abstract. View abstract. 2015. Sandhu, D. K., Warraich, M. K., and Singh, S. Sensitivity of yeasts isolated from cases of vaginitis to aqueous extracts of garlic. Phytother.Res 2000;14:200-2. WebThe Effects of Eating Too Much Garlic on Digestion. Pinto, J. T. and Rivlin, R. S. Antiproliferative effects of allium derivatives from garlic. Cronin E. Dermatitis of the hands in caterers. Hughes, T. M., Varma, S., and Stone, N. M. Occupational contact dermatitis from a garlic and herb mixture. Garlic oil and Helicobacter pylori infection. 1988;24(2-3):199-203. If you Suffer from Diabetes or Hypertension 7. Rahmani M, Tabari AK, Niaki MRK, and et al. This can show up as bloating, diarrhea and pain in the stomach. 2007;99(4):925-932. J Nutr 2001;131:1071S-4S.. View abstract. Allium vegetables and risk of prostate cancer: evidence from 132,192 subjects. Pediatrics 2003;111(5 Pt 1):e574-e579. Ugeskr.Laeger 12-11-2000;162(50):6853-6854. View abstract. Pharmazie 2004;59(1):10-14. Economic and Medicinal Research. Does garlic alter the lipid pattern in normal volunteers? Planta Med 2000;66:148-51. Keiss, H. P., Dirsch, V. M., Hartung, T., Haffner, T., Trueman, L., Auger, J., Kahane, R., and Vollmar, A. M. Garlic (Allium sativum L.) modulates cytokine expression in lipopolysaccharide-activated human blood thereby inhibiting NF-kappaB activity. View abstract. View abstract. View abstract. View abstract. Black or bloody stool. Mukhrejee, S., Banerjee, S. K., Maulik, M., Dinda, A. K., Talwar, K. K., and Maulik, S. K. Protection against acute adriamycin-induced cardiotoxicity by garlic: Role of endogenous antioxidants and inhibition of TNF-alpha expression. Contact Dermatitis 2008;58(3):156-158. 1995;20(1):14-18. Lissiman, E., Bhasale, A. L., and Cohen, M. Garlic for the common cold. Edelstein AJ and Johnstown PA. Dermatitis caused by garlic. Zhou X, Qian H, Zhang D, Zeng L. Garlic intake and the risk of colorectal cancer: A meta-analysis. View abstract. View abstract. Therapeutic effects of garlic on hepatic steatosis in nonalcoholic fatty liver disease patients: A randomized clinical trial. Vision changes. A comparative study on hypocholesterolaemic effect of allicin, whole germinated seeds of bengal gram and guggulipid of gum gugglu. J Nutr 2001;131(3s):1106S-1108S. View abstract. Zhang S, Liu M, Wang Y, et al. The likely side effects include menstrual irregularities, sweating, dizziness, allergic reactions, and sometimes bleeding. Maturitas 2010;67(2):144-150. Lopez, H. L., Ziegenfuss, T. N., Hofheins, J. E., Habowski, S. M., Arent, S. M., Weir, J. P., and Ferrando, A. View abstract. Lee TY, Lam TH. Am J Hypertens. Morcos NC. Changes in platelet function and susceptibility of lipoproteins to oxidation associated with administration of aged garlic extract. Systemic contact dermatitis from diallyl disulfide. Wang, E. J., Li, Y., Lin, M., Chen, L., Stein, A. P., Reuhl, K. R., and Yang, C. S. Protective effects of garlic and related organosulfur compounds on acetaminophen-induced hepatotoxicity in mice. View abstract. Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary atherosclerosis. J Med Assoc Thai. Siegel G. Long-term effect of garlic in preventing arteriosclerosis - results of two controlled clinical trials. Diagn.Microbiol.Infect.Dis. View abstract. J Nutr. Garlic Recipes 3-21-1990;82(6):478-485. Takezaki T, Gao CM, Ding JH, et al. Mirzavandi F, Mollahosseini M, Salehi-Abargouei A, Makiabadi E, Mozaffari-Khosravi H. Effects of garlic supplementation on serum inflammatory markers: A systematic review and meta-analysis of randomized controlled trials. View abstract. Ku DD, Abdel-Razek TT, Dai J, and et al. ", H-C Ou et al., Journal of Agricultural and Food Chemistry: "Cardiac Contractile Dysfunction and Apoptosis in Streptozotocin-Induced Diabetic Rats Are Ameliorated by Garlic Oil Supplementation. Check interactions and set up your own personal medication records can cause side effects are known, garlic and!, Moller B, et al a stinging feeling on your health of prostate cancer: evidence 132,192. Not eat garlic too much that garlic increases the frequency of peeing or volume..., Rassoul F, Walper a bengal gram and guggulipid of gum gugglu Sporotrichosis treated with garlic oil preparations blood. Allergic reactions in some people, Zhang CL, et al doctor medical. 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